Living with familial hypercholesterolemia (FH)?

In addition to adults with heterozygous FH (HeFH), PRALUENT is now approved to lower bad (LDL) cholesterol in adults with homozygous FH (HoFH) along with other cholesterol-lowering treatments.

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PRA.21.04.0005

Important update

We are disappointed to inform you that Express Scripts (ESI) has made the decision to stop covering PRALUENT on its insurance plans effective on January 1, 2021.

What does this mean for me?
  • If you are covered through an Express Scripts plan or employer, you may be asked to switch from PRALUENT to another medication. You may receive a letter from Express Scripts to notify you of this change
  • There are several health plans and employer plans associated with Express Scripts that are still covering PRALUENT, so you may not be affected
Are there options to continue my treatment on PRALUENT?
  • If your doctor determines it is in your best interest to continue treatment with PRALUENT, he/she can submit a medical exception form

Medical Exception Form

If your doctor determines it is appropriate, he/she can request a medical exception form for you to continue your treatment on PRALUENT, either through Cigna or Express Scripts depending on your prescription benefit. Your doctor would need to fill out and submit the medical exception form in its entirety, stating all relevant clinical details and the medical rationale, and provide appropriate documentation to support the use of PRALUENT.


If you have any questions, please contact us at 1-844-PRALUENT (1-844-772-5836).

What is PRALUENT® (alirocumab)?

PRALUENT is an injectable prescription medicine used:

  • in adults with cardiovascular disease to reduce the risk of heart attack, stroke, and certain types of chest pain conditions (unstable angina) requiring hospitalization.
  • along with diet, alone or together with other cholesterol-lowering medicines in adults with high blood cholesterol levels called primary hyperlipidemia (including a type of high cholesterol called heterozygous familial hypercholesterolemia), to reduce low-density lipoprotein cholesterol (LDL-C) or bad cholesterol.
  • along with other LDL-lowering treatments in adults with a type of high cholesterol called homozygous familial hypercholesterolemia who need additional lowering of LDL-C.

It is not known if PRALUENT is safe and effective in children.

Important Safety Information

Do not use PRALUENT if you are allergic to alirocumab or to any of the ingredients in PRALUENT.

Before you start using PRALUENT, tell your healthcare provider about all of your medical conditions, including allergies, and if you are pregnant or plan to become pregnant or if you are breastfeeding or plan to breastfeed.

Tell your healthcare provider or pharmacist about any medicines you take, including prescription and over-the-counter medicines, vitamins or herbal supplements.

PRALUENT can cause serious side effects, including allergic reactions that can be severe and require treatment in a hospital. Stop using PRALUENT and call your healthcare provider or go to the nearest hospital emergency room right away if you have any symptoms of an allergic reaction including a severe rash, redness, hives, severe itching, trouble breathing or swelling of the face, lips, throat, or tongue.

The most common side effects of PRALUENT include: redness, itching, swelling, or pain/tenderness at the injection site, symptoms of the common cold, and flu or flu-like symptoms. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

Talk to your doctor about the right way to prepare and give yourself a PRALUENT injection and follow the “Instructions for Use” that comes with PRALUENT.

You may report side effects to the FDA at 1-800-FDA-1088 or http://www.fda.gov/medwatch.

Click here for Full Prescribing Information for PRALUENT.

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Still have questions about PRALUENT? Get answers

FAQs
Important Safety Information

Do not use PRALUENT if you are allergic to alirocumab or to any of the ingredients in PRALUENT.

Before you start using PRALUENT, tell your healthcare provider about all of your medical conditions, including allergies, and if you are pregnant or plan to become pregnant or if you are breastfeeding or plan to breastfeed.

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