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About PRALUENT® (alirocumab)

Not an actual patient. Individual results may vary.

What is PRALUENT?

Some people need extra help managing their bad cholesterol. Statins can only do so much, but adding PRALUENT to the highest tolerated dose of a statin can help provide additional lowering of bad cholesterol. PRALUENT works differently than statins to lower bad (LDL) cholesterol. It works by blocking a protein (called PCSK9) that may contribute to high levels of bad cholesterol.

PRALUENT is an injectable medication called a PCSK9 inhibitor. It is taken every 2 weeks or 4 weeks (monthly). Click here for more information about dosing PRALUENT.

PRALUENT is used along with diet and maximally tolerated statin therapy in adults with:

Heterozygous familial hypercholesterolemia

A condition that runs in their family that causes high levels of bad (LDL) cholesterol

Atherosclerotic cardiovascular disease

Who have heart problems due to plaque buildup in their artery walls

 

Uncontrolled bad cholesterol

When the highest tolerated dose of statin is not enough to lower bad cholesterol

 

The effect of PRALUENT on heart problems such as heart attacks, stroke, or death is not known.

It is not known if PRALUENT is safe and effective in children.

Who should not use PRALUENT?

Do not use PRALUENT if you are allergic to alirocumab or to any of the ingredients in PRALUENT. For more information, click here for Full Prescribing Information.

Did you know?

PRALUENT is available in 2 different dose strengths (75 mg and 150 mg) and different dosing options. Your doctor will decide which dose is right for you and prescribe you PRALUENT every 2 weeks or 4 weeks (monthly).

Results with PRALUENT

In clinical studies of patients with heart problems due to plaque in the arteries or with HeFH whose bad (LDL) cholesterol was not at goal despite being on a healthy diet and the highest tolerated dose of a statin,

adding PRALUENT made bad cholesterol PLUNGE by an average of

Safety Information and possible side effects

PRALUENT can cause serious side effects including allergic reactions. PRALUENT may cause allergic reactions that can be severe and require treatment in a hospital. Call your doctor or go to the nearest hospital emergency room right away if you have any symptoms of an allergic reaction including a severe rash, redness, severe itching, a swollen face, or trouble breathing.

The most common side effects include:

Redness, itching, swelling, or pain/tenderness at the injection site

Symptoms of the common cold

Flu or flu-like symptoms

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all of the possible side effects of PRALUENT. Ask your doctor or pharmacist for more information. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

It is not known if PRALUENT is safe and effective in children.

What to expect with PRALUENT

A problem with high cholesterol is that you can’t feel it—so, you won’t be able to feel PRALUENT lowering your bad cholesterol. After starting PRALUENT, talk to your healthcare provider about a follow-up blood test to see where your LDL level stands.

  • When added to the highest tolerated statin dose, PRALUENT has been shown to be safe and effective in patients with atherosclerotic heart problems or heterozygous familial hypercholesterolemia (an inherited condition that causes high levels of bad cholesterol) who need additional lowering of bad cholesterol
  • The most common side effects of PRALUENT include: redness, itching, swelling, or pain/tenderness at the injection site; symptoms of the common cold; and flu or flu-like symptoms. Tell your healthcare provider if you have any side effect that bothers you or that does not go away
  • PRALUENT was generally well tolerated in 9 clinical trials and in over 2,400 patients.

Get updates on PRALUENT

Sign up to receive information about PRALUENT and how it may be able to lower your bad cholesterol.

How does PRALUENT work?

PRALUENT works differently from a statin. While statins help lower the production of bad (LDL) cholesterol, PRALUENT helps remove it from the bloodstream.

Though they work differently, PRALUENT and statins work together to lower your bad cholesterol, when added to a healthy diet.

Before starting PRALUENT

It’s important you tell your doctor about all of your medical conditions, including allergies, and if you are:

Pregnant or plan to become pregnant. It is not known if PRALUENT will harm your unborn baby. Tell your doctor if you become pregnant while taking PRALUENT.

Breastfeeding or plan to breastfeed. You and your doctor should decide if you will take PRALUENT or breastfeed. You should not do both without talking to your doctor first.

There is a pregnancy registry for women who take PRALUENT during pregnancy. The purpose of this registry is to collect information about your health and your baby’s health. You can talk to your healthcare provider or contact 1-877-311-8972 or go to https://mothertobaby.org/ongoing-study/praluent/ to enroll in this registry or get more information.

Tell your doctor or pharmacist about any prescription and over-the-counter medicines you are taking or plan to take, including natural or herbal remedies.

Is PRALUENT right for me?

Be prepared for your next doctor visit. Answer a few questions to get your customized guide.

Additional information

Speak to a care specialist

For more information about PRALUENT, call 1-844-PRALUENT (1-844-772-5836).

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. DO NOT use PRALUENT for a condition for which it was not prescribed. DO NOT give PRALUENT to other people, even if they have the same symptoms that you have. It may harm them.

The Patient Information leaflet summarizes the most important information about PRALUENT. If you would like more information, talk with your doctor. You can ask your pharmacist or doctor for information about PRALUENT that is written for health professionals.

Download information about PRALUENT

Important Safety Information

Do not use PRALUENT if you are allergic to alirocumab or to any of the ingredients in PRALUENT.

Before starting PRALUENT, tell your healthcare provider about all your medical conditions, including allergies, and if you are pregnant or plan to become pregnant or if you are breastfeeding or plan to breastfeed.

Tell your healthcare provider or pharmacist about any prescription and over-the-counter medicines you are taking or plan to take, including natural or herbal remedies.

PRALUENT can cause serious side effects, including allergic reactions that can be severe and require treatment in a hospital. Call your healthcare provider or go to the nearest emergency room right away if you have any symptoms of an allergic reaction, including a severe rash, redness, severe itching, a swollen face, or trouble breathing.

The most common side effects of PRALUENT include: redness, itching, swelling, or pain/tenderness at the injection site, symptoms of the common cold, and flu or flu-like symptoms. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

Talk to your healthcare provider about the right way to prepare and give yourself a PRALUENT injection and follow the "Instructions for Use" that comes with PRALUENT.

You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

What is PRALUENT® (alirocumab)?

PRALUENT is an injectable prescription medicine called a PCSK9 inhibitor. PRALUENT is used along with diet and maximally tolerated statin therapy in adults with heterozygous familial hypercholesterolemia (an inherited condition that causes high levels of LDL) or atherosclerotic heart problems, who need additional lowering of LDL cholesterol.

The effect of PRALUENT on heart problems such as heart attacks, stroke, or death is not known.

It is not known if PRALUENT is safe and effective in children.

Click here for Full Prescribing Information for PRALUENT.

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BrandX® is a long-acting human insulin analog indicated to improve glycemic control in adults with diabetes mellitus. BrandX® should be administered subcutaneously once a day at the same time every day. Important Limitations of Use: BrandX® is not recommended for treating diabetic ketoacidosis. Use intravenous, short-acting insulin instead. 

a"Certified Diabetes Educator" and "CDE" are certification marks owned and registered by the National Certification Board for Diabetes Educators (NCBDE). NCBDE is not affiliated in any way with Sanofi US. NCBDE does not sponsor or endorse any diabetes-related products or services.

 


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SAUS.PRL.18.07.3872a Last Updated: July 2018

Important Safety Information

Do not use PRALUENT if you are allergic to alirocumab or to any of the ingredients in PRALUENT.

Before starting PRALUENT, tell your healthcare provider about all your medical conditions, including allergies, and if you
are pregnant or plan to become pregnant or if you are breastfeeding or plan to breastfeed.

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